Recurrent radiation necrosis in the brain following stereotactic radiosurgery.
نویسندگان
چکیده
Harvard Medical School, Boston, Massachusetts Department of Neurosurgery, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Pathology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts York Hospital Oncology, York, Maine Department of Medical Oncology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Radiation Oncology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts
منابع مشابه
Radiation Necrosis – A Growing Problem in a Case of Brain Metastases Following Whole Brain Radiotherapy and Stereotactic Radiosurgery
Stereotactic radiosurgery (SRS) provides excellent control in the treatment of brain metastases (BM). The use of newer, targeted and immunotherapy treatments have resulted in improved overall survival in patients even with an extensive metastatic disease. Hence, it is increasingly important to consider the potential for late toxicities like radiation-induced necrosis (RN) of the brain. We prese...
متن کاملWe've Got a Treatment, but What's the Disease? Or A Brief History of Hypofractionation and Its Relationship to Stereotactic Radiosurgery.
Hypofractionation has been a recurring issue during the near century-long history of radiation oncology. Coutard first introduced protracted dose-fraction regimens that uniquely allowed for the control of "deep" tumors. Subsequent studies have consistently shown that hypofractionation leads to an increase in complication rates and a paradoxical decrease in cure rates. There have, nonetheless, b...
متن کاملWe’ve Got a Treatment, but What’s the Disease?
Hypofractionation has been a recurring issue during the near century-long history of radiation oncology. Coutard first introduced protracted dose-fraction regimens that uniquely allowed for the control of “deep” tumors. Subsequent studies have consistently shown that hypofractionation leads to an increase in complication rates and a paradoxical decrease in cure rates. There have, nonetheless, b...
متن کاملStereotactic radiosurgery to the resection cavity of brain metastases: a retrospective analysis and literature review.
PURPOSE The aim of this study was to analyze results of stereotactic radiosurgery (SRS) as adjuvant therapy for resected brain metastases. METHODS Medical records of patients treated at a single institution with SRS to the postoperative cavity of brain metastases were retrospectively reviewed. Patients who completed the prescribed SRS regimen following gross-total resection and had no previou...
متن کاملRadiation necrosis masquerading as late tumor recurrence: 14 years after combined fractionated stereotactic radiosurgery and conventional radiation therapy
Radiation necrosis is a known sequela of delivering high doses of ionizing radiation to the central nervous system and may be confused with tumor recurrence. Although stereotactic radiation has found increasing application in managing central nervous system malignancies, the imaging appearance of benign tissue several years after such treatment has not been frequently documented in the medical ...
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عنوان ژورنال:
- Practical radiation oncology
دوره 5 3 شماره
صفحات -
تاریخ انتشار 2015